human HNF1A shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HNF1A

Gene Name

HNF1 homeobox A

Gene ID

6927

Gene Synonyms

HNF-1A; HNF1; IDDM20; LFB1; MODY3; TCF-1; TCF1

ORF Size

1896 bp

RefSeq#

NM_000545

Gene Description

HNF1A is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.

UniGene ID

Hs.654455

HGNC ID

HGNC:11621