human HHIP shRNA silencing Adenovirus

Cat. No: shADV-211005

Availability: 5-8 weeks

Name: Ad-h-HHIP-shRNA

This is an Adenovirus expressing shRNA for silencing of Human HHIP.

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Species: Human
Gene Symbol: HHIP
Gene Name: hedgehog interacting protein
Gene ID: 64399
Gene Synonyms: HIP
ORF Size: 2103 bp
RefSeq#: NM_022475
Gene Description: HHIP encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.
UniGene ID: Hs.507991
HGNC ID: HGNC:14866