human HELZ shRNA silencing Adenovirus

Product Info

Knockdown

>60% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HELZ

Gene Name

helicase with zinc finger

Gene ID

9931

Gene Synonyms

DHRC; DRHC; HUMORF5

ORF Size

5829 bp

RefSeq#

NM_014877

Gene Description

HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 (PubMed 10471385)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.569824

HGNC ID

HGNC:16878