human GYG1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GYG1

Gene Name

glycogenin 1

Gene ID

2992

Gene Synonyms

GSD15; GYG

ORF Size

1002 bp

RefSeq#

NM_004130

Gene Description

GYG1 encodes a member of the glycogenin family. Glycogenin is a glycosyltransferase that catalyzes the formation of a short glucose polymer from uridine diphosphate glucose in an autoglucosylation reaction. This reaction is followed by elongation and branching of the polymer, catalyzed by glycogen synthase and branching enzyme, to form glycogen. GYG1 is expressed in muscle and other tissues. Mutations in this gene result in glycogen storage disease XV. GYG1 has pseudogenes on chromosomes 1, 8 and 13 respectively. Alternatively spliced transcript variants encoding different isoforms have been identified.

UniGene ID

Hs.477892

HGNC ID

HGNC:4699