human GPD2 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GPD2

Gene Name

glycerol-3-phosphate dehydrogenase 2

Gene ID

2820

Gene Synonyms

GDH2; GPDM; mGPDH

ORF Size

1137 bp

RefSeq#

NM_000408

Gene Description

GPD2 localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.

UniGene ID

Hs.512382

HGNC ID

HGNC:4456