human GOT1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GOT1

Gene Name

glutamic-oxaloacetic transaminase 1

Gene ID

2805

Gene Synonyms

AST1; ASTQTL1; cAspAT; cCAT; GIG18

ORF Size

1242 bp

RefSeq#

NM_002079

Gene Description

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.

UniGene ID

Hs.500756

HGNC ID

HGNC:4432