human GLRX shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-209995
Availability:
3-5 weeks
Name:
Ad-h-GLRX-shRNA
This is an Adenovirus expressing shRNA for silencing of Human GLRX.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GLRX
- Gene Name
- glutaredoxin
- Gene ID
- 2745
- Gene Synonyms
- GRX; GRX1
- ORF Size
- 321 bp
- RefSeq#
- NM_002064
- Gene Description
- GLRX encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
- UniGene ID
- Hs.712696
- HGNC ID
- HGNC:4330
Related Products
Product | Cat No. |
---|---|
AAV-h-GLRX | AAV-209995 |
AAV-m-GLRX | AAV-260203 |
Ad-h-GLRX | ADV-209995 |
Ad-m-GLRX | ADV-260203 |
AAV-h-GLRX-shRNA | shAAV-209995 |
AAV-m-GLRX-shRNA | shAAV-260203 |
Ad-m-GLRX-shRNA | shADV-260203 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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