human GDF15 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GDF15

Gene Name

growth differentiation factor 15

Gene ID

9518

Gene Synonyms

GDF-15; MIC-1; MIC1; NAG-1; PDF; PLAB; PTGFB

ORF Size

927 bp

RefSeq#

NM_004864

Gene Description

Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.(supplied by OMIM, Oct 2009)

UniGene ID

Hs.616962

HGNC ID

HGNC:30142