human GAD2 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-209539
Availability:
5-8 weeks
Name:
Ad-h-GAD2-shRNA
This is an Adenovirus expressing shRNA for silencing of Human GAD2.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GAD2
- Gene Name
- glutamate decarboxylase 2
- Gene ID
- 2572
- Gene Synonyms
- GAD65
- ORF Size
- 1758 bp
- RefSeq#
- NM_000818
- Gene Description
- GAD2 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. GAD2 may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
- UniGene ID
- Hs.231829
- HGNC ID
- HGNC:4093
Related Products
Product | Cat No. |
---|---|
AAV-h-GAD2 | AAV-209539 |
AAV-m-GAD2 | AAV-259826 |
Ad-h-GAD2 | ADV-209539 |
Ad-m-GAD2 | ADV-259826 |
AAV-h-GAD2-shRNA | shAAV-209539 |
AAV-m-GAD2-shRNA | shAAV-259826 |
Ad-m-GAD2-shRNA | shADV-259826 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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