human FAM38B shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PIEZO2

Gene Name

piezo type mechanosensitive ion channel component 2

Gene ID

63895

Gene Synonyms

C18orf30; C18orf58; DA3; DA5; DAIPT; FAM38B; FAM38B2; HsT748; HsT771; MWKS

ORF Size

1632 bp

RefSeq#

NM_022068

Gene Description

Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The PIEZO2 protein has a role in rapidly adapting mechanically activated (MA) currents in somatosensory neurons (Coste et al., 2010 (PubMed 20813920)).(supplied by OMIM, Nov 2010)

UniGene ID

Hs.585839

HGNC ID

HGNC:26270