human EIF3J shRNA silencing Adenovirus

Product Info

Knockdown

>60% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

EIF3J

Gene Name

eukaryotic translation initiation factor 3 subunit J

Gene ID

8669

Gene Synonyms

eIF3-alpha; eIF3-p35; EIF3S1

ORF Size

777 bp

RefSeq#

NM_003758

Gene Description

Eukaryotic initiation factor-3 (EIF3) has a molecular mass of about 600 kD and contains 13 nonidentical protein subunits, including EIF3J. EIF3 plays a central role in binding of initiator methionyl-tRNA and mRNA to the 40S ribosomal subunit to form the 40S initiation complex (Fraser et al., 2004 (PubMed 14688252); Fraser et al., 2007 (PubMed 17588516)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.404056

HGNC ID

HGNC:3270