human EFEMP1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

EFEMP1

Gene Name

EGF containing fibulin like extracellular matrix protein 1

Gene ID

2202

Gene Synonyms

DHRD; DRAD; FBLN3; FBNL; FIBL-3; MLVT; MTLV; S1-5

ORF Size

1482 bp

RefSeq#

NM_001039348

Gene Description

EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. EFEMP1 is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.

UniGene ID

Hs.76224

HGNC ID

HGNC:3218