human EDN1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

EDN1

Gene Name

endothelin 1

Gene ID

1906

Gene Synonyms

ARCND3; ET1; HDLCQ7; PPET1; QME

ORF Size

639 bp

RefSeq#

NM_001955

Gene Description

EDN1 is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.713645

HGNC ID

HGNC:3176