human CXCR7 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ACKR3

Gene Name

atypical chemokine receptor 3

Gene ID

57007

Gene Synonyms

CMKOR1; CXC-R7; CXCR-7; CXCR7; GPR159; RDC-1; RDC1

ORF Size

1089 bp

RefSeq#

NM_020311

Gene Description

CXCR7 encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

UniGene ID

Hs.471751

HGNC ID

HGNC:23692