human CX3CR1 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CX3CR1

Gene Name

C-X3-C motif chemokine receptor 1

Gene ID

1524

Gene Synonyms

CCRL1; CMKBRL1; CMKDR1; GPR13; GPRV28; V28

ORF Size

1068 bp

RefSeq#

NM_001337

Gene Description

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.

UniGene ID

Hs.78913

HGNC ID

HGNC:2558