human CRLF1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CRLF1

Gene Name

cytokine receptor like factor 1

Gene ID

9244

Gene Synonyms

CISS; CISS1; CLF; CLF-1; NR6; zcytor5

ORF Size

1269 bp

RefSeq#

NM_004750

Gene Description

CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.

UniGene ID

Hs.114948

HGNC ID

HGNC:2364