human CPSF3 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CPSF3

Gene Name

cleavage and polyadenylation specific factor 3

Gene ID

51692

Gene Synonyms

CPSF-73; CPSF73

ORF Size

2055 bp

RefSeq#

NM_016207

Gene Description

Most eukaryotic mRNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunit of the cleavage and polyadenylation specificity factor (CPSF) and is the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al., 2006 (PubMed 17128255)).(supplied by OMIM, Jul 2010)

UniGene ID

Hs.515972

HGNC ID

HGNC:2326