human CHMP5 shRNA silencing Adenovirus

Cat. No: shADV-205168

Availability: 5-8 weeks

Name: Ad-h-CHMP5-shRNA

This is an Adenovirus expressing shRNA for silencing of Human CHMP5.

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Species: Human
Gene Symbol: CHMP5
Gene Name: charged multivesicular body protein 5
Gene ID: 51510
Gene Synonyms: C9orf83; CGI-34; HSPC177; PNAS-2; SNF7DC2; Vps60
ORF Size: 660 bp
RefSeq#: NM_016410
Gene Description: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 (PubMed 16730941)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.635313
HGNC ID: HGNC:26942