human CCR4 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

CCR4

Gene Name

C-C motif chemokine receptor 4

Gene ID

1233

Gene Synonyms

CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5

ORF Size

1083 bp

RefSeq#

NM_005508

Gene Description

CCR4 belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

UniGene ID

Hs.184926

HGNC ID

HGNC:1605