human C7ORF16 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PPP1R17

Gene Name

protein phosphatase 1 regulatory subunit 17

Gene ID

10842

Gene Synonyms

C7orf16; GSBS

ORF Size

468 bp

RefSeq#

NM_006658

Gene Description

PPP1R17 is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.227011

HGNC ID

HGNC:16973