human BRP44L shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MPC1

Gene Name

mitochondrial pyruvate carrier 1

Gene ID

51660

Gene Synonyms

BRP44L; CGI-129; dJ68L15.3; MPYCD

ORF Size

330 bp

RefSeq#

NM_016098

Gene Description

MPC1 is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene.

UniGene ID

Hs.172755

HGNC ID

HGNC:21606