human BLOC1S1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

BLOC1S1

Gene Name

biogenesis of lysosomal organelles complex 1 subunit 1

Gene ID

2647

Gene Synonyms

BLOS1; BORCS1; GCN5L1; MICoA; RT14

ORF Size

378 bp

RefSeq#

NM_001487

Gene Description

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 (PubMed 15102850)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.94672

HGNC ID

HGNC:4200