human BDP1 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

BDP1

Gene Name

B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

Gene ID

55814

Gene Synonyms

HSA238520; TAF3B1; TFC5; TFIIIB''; TFIIIB150; TFIIIB90; TFNR

ORF Size

7875 bp

RefSeq#

NM_018429

Gene Description

The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription.

UniGene ID

Hs.258272

HGNC ID

HGNC:13652