human BBS4 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-201999
Availability:
5-8 weeks
Name:
Ad-h-BBS4-shRNA
This is an Adenovirus expressing shRNA for silencing of Human BBS4.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- BBS4
- Gene Name
- Bardet-Biedl syndrome 4
- Gene ID
- 585
- ORF Size
- 1560 bp
- RefSeq#
- NM_033028
- Gene Description
- BBS4 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein 'BBSome' complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.
- UniGene ID
- Hs.208681
- HGNC ID
- HGNC:969
Related Products
Product | Cat No. |
---|---|
AAV-h-BBS4 | AAV-201999 |
AAV-m-BBS4 | AAV-253660 |
Ad-h-BBS4 | ADV-201999 |
Ad-m-BBS4 | ADV-253660 |
AAV-h-BBS4-shRNA | shAAV-201999 |
AAV-m-BBS4-shRNA | shAAV-253660 |
Ad-m-BBS4-shRNA | shADV-253660 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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