human BBOX1 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

BBOX1

Gene Name

gamma-butyrobetaine hydroxylase 1

Gene ID

8424

Gene Synonyms

BBH; BBOX; G-BBH; gamma-BBH

ORF Size

1164 bp

RefSeq#

NM_003986

Gene Description

BBOX1 encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.

UniGene ID

Hs.591996

HGNC ID

HGNC:964