human BACE1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-201929
Availability:
3-5 weeks
Name:
Ad-h-BACE1-shRNA
This is an Adenovirus expressing shRNA for silencing of Human BACE1.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- BACE1
- Gene Name
- beta-secretase 1
- Gene ID
- 23621
- Gene Synonyms
- ASP2; BACE; HSPC104
- ORF Size
- 1506 bp
- RefSeq#
- NM_012104
- Gene Description
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
- UniGene ID
- Hs.504003
- HGNC ID
- HGNC:933
Related Products
Product | Cat No. |
---|---|
AAV-h-BACE1 | AAV-201929 |
AAV-m-BACE1 | AAV-253587 |
Ad-h-BACE1 | ADV-201929 |
Ad-m-BACE1 | ADV-253587 |
AAV-h-BACE1-shRNA | shAAV-201929 |
AAV-m-BACE1-shRNA | shAAV-253587 |
Ad-m-BACE1-shRNA | shADV-253587 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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