human ASB7 shRNA silencing Adenovirus

Cat. No: shADV-201535

Availability: 3-5 weeks

Name: Ad-h-ASB7-shRNA

This is an Adenovirus expressing shRNA for silencing of Human ASB7.

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Species: Human
Gene Symbol: ASB7
Gene Name: ankyrin repeat and SOCS box containing 7
Gene ID: 140460
ORF Size: 825 bp
RefSeq#: NM_024708
Gene Description: ASB7 belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
UniGene ID: Hs.709044
HGNC ID: HGNC:17182