human AGXT shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AGXT

Gene Name

alanine-glyoxylate aminotransferase

Gene ID

189

Gene Synonyms

AGT; AGT1; AGXT1; PH1; SPAT; SPT; TLH6

ORF Size

1179 bp

RefSeq#

NM_000030

Gene Description

AGXT is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.

UniGene ID

Hs.144567

HGNC ID

HGNC:341