human AFF2 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AFF2

Gene Name

AF4/FMR2 family member 2

Gene ID

2334

Gene Synonyms

FMR2; FMR2P; FRAXE; MRX2; OX19

ORF Size

3906 bp

RefSeq#

NM_002025

Gene Description

AFF2 encodes a putative transcriptional activator that is a member of the AF4\FMR2 gene family. AFF2 is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.

UniGene ID

Hs.496911

HGNC ID

HGNC:3776