human ADIPOR1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ADIPOR1

Gene Name

adiponectin receptor 1

Gene ID

51094

Gene Synonyms

ACDCR1; CGI-45; CGI45; PAQR1; TESBP1A

ORF Size

1128 bp

RefSeq#

NM_015999

Gene Description

ADIPOR1 encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14.

UniGene ID

Hs.5298

HGNC ID

HGNC:24040