human ACSS2 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ACSS2

Gene Name

acyl-CoA synthetase short-chain family member 2

Gene ID

55902

Gene Synonyms

ACAS2; ACECS; ACS; ACSA; dJ1161H23.1

ORF Size

2106 bp

RefSeq#

NM_018677

Gene Description

ACSS2 encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.517034

HGNC ID

HGNC:15814