human AASDHPPT shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AASDHPPT

Gene Name

aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Gene ID

60496

Gene Synonyms

AASD-PPT; ACPS; CGI-80; LYS2; LYS5

ORF Size

930 bp

RefSeq#

NM_015423

Gene Description

AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.

UniGene ID

Hs.524009

HGNC ID

HGNC:14235