human A2ML1 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

A2ML1

Gene Name

alpha-2-macroglobulin like 1

Gene ID

144568

Gene Synonyms

CPAMD9

ORF Size

4365 bp

RefSeq#

NM_144670

Gene Description

A2ML1 encodes a member of the alpha-macroglobulin superfamily. The encoded protein acts as an inhibitor for several proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID: 20805888). Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.620532

HGNC ID

HGNC:23336