rat HMGN1 shRNA silencing AAV

Cat. No: shAAV-295184

Availability: 6-8 weeks

Name: AAV-r-HMGN1-shRNA

This is an AAV expressing shRNA for silencing of Rat Hmgn1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Hmgn1
Gene Name: high mobility group nucleosome binding domain 1
Gene ID: 360704
ORF Size: 291 bp
RefSeq#: NM_001013184
Gene Description: Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity).