rat PPP1R10 shRNA silencing AAV

Cat. No: shAAV-295173

Availability: 6-8 weeks

Name: AAV-r-PPP1R10-shRNA

This is an AAV expressing shRNA for silencing of Rat Ppp1r10.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Ppp1r10
Gene Name: protein phosphatase 1, regulatory subunit 10
Gene ID: 65045
Gene Synonyms: Fb19; Pnuts
ORF Size: 2619 bp
RefSeq#: NM_022951
Gene Description: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).