rat BCO2 shRNA silencing AAV

Cat. No: shAAV-295170

Availability: 6-8 weeks

Name: AAV-r-BCO2-shRNA

This is an AAV expressing shRNA for silencing of Rat Bco2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Bco2
Gene Name: beta-carotene oxygenase 2
Gene ID: 315644
Gene Synonyms: Ab2-079; Bcdo2
ORF Size: 1599 bp
RefSeq#: NM_001127712
Gene Description: Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects.