rat AEBP1 shRNA silencing AAV

Cat. No: shAAV-295166

Availability: 4-5 weeks

Name: AAV-r-AEBP1-shRNA

This is an AAV expressing shRNA for silencing of Rat Aebp1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Aebp1
Gene Name: AE binding protein 1
Gene ID: 305494
ORF Size: 3387 bp
RefSeq#: NM_001100970
Gene Description: AEBP1 may positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation (By similarity). May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness (By similarity). Can act as a transcriptional repressor (By similarity).