rat PSRC1 shRNA silencing AAV

Cat. No: shAAV-294915

Availability: 4-5 weeks

Name: AAV-r-PSRC1-shRNA

This is an AAV expressing shRNA for silencing of Rat Psrc1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Psrc1
Gene Name: proline and serine rich coiled-coil 1
Gene ID: 691380
ORF Size: 990 bp
RefSeq#: NM_001044302
Gene Description: Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.