rat SLC11A2 shRNA silencing AAV

Cat. No: shAAV-294613

Availability: 4-5 weeks

Name: AAV-r-SLC11A2-shRNA

This is an AAV expressing shRNA for silencing of Rat Slc11a2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Slc11a2
Gene Name: solute carrier family 11 member 2
Gene ID: 25715
Gene Synonyms: Dmt1; Nramp2
ORF Size: 1479 bp
RefSeq#: NM_013173
Gene Description: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution.