rat ERCC3 shRNA silencing AAV

Cat. No: shAAV-294245

Availability: 4-5 weeks

Name: AAV-r-ERCC3-shRNA

This is an AAV expressing shRNA for silencing of Rat Ercc3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Ercc3
Gene Name: ERCC excision repair 3, TFIIH core complex helicase subunit
Gene ID: 291703
ORF Size: 2349 bp
RefSeq#: NM_001031644
Gene Description: ATP-dependent 3'-5' DNA helicase, component of the core-TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage.