rat CHAF1B shRNA silencing AAV

Cat. No: shAAV-293950

Availability: 4-5 weeks

Name: AAV-r-CHAF1B-shRNA

This is an AAV expressing shRNA for silencing of Rat Chaf1b.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Chaf1b
Gene Name: chromatin assembly factor 1 subunit B
Gene ID: 288242
ORF Size: 1719 bp
RefSeq#: NM_001024741
Gene Description: Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. The CCR4-NOT complex functions as general transcription regulation complex.