rat KLKB1 shRNA silencing AAV

Cat. No: shAAV-293572

Availability: 6-8 weeks

Name: AAV-r-KLKB1-shRNA

This is an AAV expressing shRNA for silencing of Rat Klkb1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Klkb1
Gene Name: kallikrein B1
Gene ID: 25048
Gene Synonyms: Kalp1; KALP15; Klk3; PK
ORF Size: 1917 bp
RefSeq#: NM_012725
Gene Description: The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.