rat HMOX1 shRNA silencing AAV

Cat. No: shAAV-293308

Availability: 6-8 weeks

Name: AAV-r-HMOX1-shRNA

This is an AAV expressing shRNA for silencing of Rat Hmox1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Hmox1
Gene Name: heme oxygenase 1
Gene ID: 24451
Gene Synonyms: Heox; HEOXG; Hmox; Ho-1; Ho1; hsp32
ORF Size: 870 bp
RefSeq#: NM_012580
Gene Description: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed.