rat LGALS3 shRNA silencing AAV

Cat. No: shAAV-293218

Availability: 6-8 weeks

Name: AAV-r-LGALS3-shRNA

This is an AAV expressing shRNA for silencing of Rat Lgals3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Lgals3
Gene Name: galectin 3
Gene ID: 83781
Gene Synonyms: AGE-R3; CBP30; gal-3; L-34
ORF Size: 789 bp
RefSeq#: NM_031832
Gene Description: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.