rat BCL2L1 shRNA silencing AAV

Cat. No: shAAV-292984

Availability: 4-5 weeks

Name: AAV-r-BCL2L1-shRNA

This is an AAV expressing shRNA for silencing of Rat Bcl2l1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Bcl2l1
Gene Name: Bcl2-like 1
Gene ID: 24888
Gene Synonyms: bcl-X; Bcl-xl; Bcl2l; Bclx
ORF Size: 702 bp
RefSeq#: NM_001033670
Gene Description: Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis|Function: Isoform Bcl-X(S) promotes apoptosis.