rat SLC46A1 shRNA silencing AAV

Cat. No: shAAV-292851

Availability: 6-8 weeks

Name: AAV-r-SLC46A1-shRNA

This is an AAV expressing shRNA for silencing of Rat Slc46a1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Slc46a1
Gene Name: solute carrier family 46 member 1
Gene ID: 303333
Gene Synonyms: RGD1309472
ORF Size: 1380 bp
RefSeq#: NM_001013969
Gene Description: Has been shown to act both as an intestinal proton-coupled high-affinity folate transporter and as an intestinal heme transporter which mediates heme uptake from the gut lumen into duodenal epithelial cells. The iron is then released from heme and may be transported into the bloodstream. Dietary heme iron is an important nutritional source of iron. Shows a higher affinity for folate than heme.