rat CBX3 shRNA silencing AAV

Cat. No: shAAV-292413

Availability: 4-5 weeks

Name: AAV-r-CBX3-shRNA

This is an AAV expressing shRNA for silencing of Rat Cbx3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Cbx3
Gene Name: chromobox 3
Gene ID: 297093
Gene Synonyms: Hp1-gamma
ORF Size: 552 bp
RefSeq#: NM_001008313
Gene Description: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.