rat C1QC shRNA silencing AAV

Cat. No: shAAV-292218

Availability: 6-8 weeks

Name: AAV-r-C1QC-shRNA

This is an AAV expressing shRNA for silencing of Rat C1qc.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: C1qc
Gene Name: complement C1q C chain
Gene ID: 362634
Gene Synonyms: C1qg
ORF Size: 738 bp
RefSeq#: NM_001008524
Gene Description: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.