rat RAC2 shRNA silencing AAV

Cat. No: shAAV-292209

Availability: 6-8 weeks

Name: AAV-r-RAC2-shRNA

This is an AAV expressing shRNA for silencing of Rat Rac2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Rac2
Gene Name: ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
Gene ID: 366957
ORF Size: 579 bp
RefSeq#: NM_001008384
Gene Description: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.