rat ACE shRNA silencing AAV

Cat. No: shAAV-292169

Availability: 6-8 weeks

Name: AAV-r-ACE-shRNA

This is an AAV expressing shRNA for silencing of Rat Ace.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Ace
Gene Name: angiotensin I converting enzyme
Gene ID: 24310
Gene Synonyms: CD143; Dcp1; StsRR92
ORF Size: 3942 bp
RefSeq#: NM_012544
Gene Description: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.